Detection of Sugar Chain Expression in Hydatidiform Mole Using Lectin Histochemistry

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detection of sugar chain expression in hydatidiform mole using lectin histochemistry

conclusions our histochemical findings showed a relatively heavy glycosylation of syncytiotrophoblasts of both partial and complete molar tissues, which was prominent in apical portion. this may play a role in their capacity to increase trophoblastic proliferation. results the partial and complete moles generally showed similar reactivity with all used lectins. none of lectins reacted with vill...

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Detection of Sugar Chain Expression in Hydatidiform Mole Using Lectin Histochemistry

BACKGROUND Hydatidiform moles carry a significant risk for developing persistent gestational trophoblastic disease. Lectins are useful tools to identify cellular glycosylation pattern and changes in glycosylation that occur during growth, development, differentiation and also, during disease states. OBJECTIVES Considering the changes in glycosylation that occur during cell proliferation, diff...

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Detection of Glycoconjugate Changes in the Embryonic Trigeminal Nucleus in Balb/C Mouse by Lectin Histochemistry

Purpose: Determination of changes of glycoconjugates, which have special terminal sugars, in embryonic developmental processes of brain stem and trigeminal nucleus in Balb/C mouse. Materials and Methods: In this study mice embryos between 10-17 embryonic days were used. They were fixed according to ordinary laboratory procedures. The specimens were embedded in paraffin and serial sections with...

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Understanding hydatidiform mole.

Hydatidiform mole (often referred to as molar pregnancy) is the most common disorder in a category of pathologies known as Gestational Trophoblastic Diseases that are associated with abnormal fertilization in pregnancy. Current practices in screening and monitoring during early pregnancy allow for better identification of hydatidiform mole, sometimes prior to the onset of significant symptoms.O...

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Recurrent partial hydatidiform mole.

Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pr...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2013

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.3997